Novel 5′-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents

A series of novel 5′-norcarbocyclic derivatives of 5-alkoxymethyl or 5-alkyltriazolyl-methyl uracil were synthesized and the activity of the compounds evaluated against both Gram-positive and Gram-negative bacteria. The growth of Mycobacterium smegmatis was completely inhibited by the most active co...

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Pubblicato in:Molecules
Autori principali: Khandazhinskaya, Anastasia L., Alexandrova, Liudmila A., Matyugina, Elena S., Solyev, Pavel N., Efremenkova, Olga V., Buckheit, Karen W., Wilkinson, Maggie, Buckheit, Robert W., Chernousova, Larisa N., Smirnova, Tatiana G., Andreevskaya, Sofya N., Leonova, Olga G., Popenko, Vladimir I., Kochetkov, Sergey N., Seley-Radtke, Katherine L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321083/
https://ncbi.nlm.nih.gov/pubmed/30477147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123069
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