Novel 5′-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents

A series of novel 5′-norcarbocyclic derivatives of 5-alkoxymethyl or 5-alkyltriazolyl-methyl uracil were synthesized and the activity of the compounds evaluated against both Gram-positive and Gram-negative bacteria. The growth of Mycobacterium smegmatis was completely inhibited by the most active co...

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Gepubliceerd in:Molecules
Hoofdauteurs: Khandazhinskaya, Anastasia L., Alexandrova, Liudmila A., Matyugina, Elena S., Solyev, Pavel N., Efremenkova, Olga V., Buckheit, Karen W., Wilkinson, Maggie, Buckheit, Robert W., Chernousova, Larisa N., Smirnova, Tatiana G., Andreevskaya, Sofya N., Leonova, Olga G., Popenko, Vladimir I., Kochetkov, Sergey N., Seley-Radtke, Katherine L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321083/
https://ncbi.nlm.nih.gov/pubmed/30477147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123069
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