Synthesis of Multi-Substituted Pyrrole Derivatives Through [3+2] Cycloaddition with Tosylmethyl Isocyanides (TosMICs) and Electron-Deficient Compounds

Pyrrole and its polysubstituted derivatives are important five-membered heterocyclic compounds, which exist alone or as a core framework in many pharmaceutical and natural product structures, some of which have good biological activities. The Van Leusen [3+2] cycloaddition reaction based on tosylmet...

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Bibliographic Details
Published in:Molecules
Main Authors: Ma, Zhengning, Ma, Zicheng, Zhang, Dawei
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222313/
https://ncbi.nlm.nih.gov/pubmed/30336556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102666
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