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Alkyl Sulfinates: Formal Nucleophiles for Synthesizing TosMIC Analogs

Alkyl sulfinates function as formal nucleophiles in Mannich-type reactions to give sulfonyl formamides, which are readily dehydrated to the corresponding sulfonylmethyl isonitriles. The efficient, two-step synthesis provides a general route to sulfonylmethyl isonitriles from readily available methyl...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Lujan-Montelongo, J. Armando, Estevez, Angel Ojeda, Fleming, Fraser F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520545/
https://ncbi.nlm.nih.gov/pubmed/26236153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201403615
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