Hepatic cell sheets engineered from human mesenchymal stem cells with a single small molecule compound IC-2 ameliorate acute liver injury in mice

INTRODUCTION: We previously reported that transplantation of hepatic cell sheets from human bone marrow-derived mesenchymal stem cells (BM-MSCs) with hexachlorophene, a Wnt/β-catenin signaling inhibitor, ameliorated acute liver injury. In a further previous report, we identified IC-2, a newly synthe...

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Pubblicato in:Regen Ther
Autori principali: Itaba, Noriko, Noda, Ikuya, Oka, Hiroyuki, Kono, Yohei, Okinaka, Kaori, Yokobata, Tsuyoshi, Okazaki, Shizuma, Morimoto, Minoru, Shiota, Goshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japanese Society for Regenerative Medicine 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222293/
https://ncbi.nlm.nih.gov/pubmed/30525075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2018.07.001
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