Mouse Model of Poorly Differentiated Thyroid Carcinoma Driven by STRN-ALK Fusion

Chromosomal rearrangements of the ALK gene, which lead to constitutive activation of ALK tyrosine kinase, are found in various cancers. In thyroid cancers, ALK fusions, most commonly the STRN-ALK fusion, are detected in papillary thyroid cancer and with higher frequency in poorly differentiated and...

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Udgivet i:Am J Pathol
Main Authors: Nikitski, Alyaksandr V., Rominski, Susan L., Wankhede, Mamta, Kelly, Lindsey M., Panebianco, Federica, Barila, Guillermo, Altschuler, Daniel L., Nikiforov, Yuri E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222272/
https://ncbi.nlm.nih.gov/pubmed/30125543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.07.012
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