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Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

Background: Although primarily a neurodegenerative process, there is increasing awareness of peripheral disease mechanisms in Parkinson's disease. To investigate disease processes in accessible patient cells, we studied peripheral blood mononuclear cells in recently diagnosed PD patients and ra...

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Dettagli Bibliografici
Pubblicato in:Mov Disord
Autori principali: Smith, Amy M., Depp, Constanze, Ryan, Brent J., Johnston, Geoffrey I., Alegre‐Abarrategui, Javier, Evetts, Samuel, Rolinski, Michal, Baig, Fahd, Ruffmann, Claudio, Simon, Anna Katharina, Hu, Michele T. M., Wade‐Martins, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221131/
https://ncbi.nlm.nih.gov/pubmed/30294923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.104
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