Syndecan‐4 influences mammalian myoblast proliferation by modulating myostatin signalling and G1/S transition

Myostatin, a TGF‐β superfamily member, is a negative regulator of muscle growth. Here we describe how myostatin activity is regulated by syndecan‐4, a ubiquitous transmembrane heparan sulfate proteoglycan. During muscle regeneration the levels of both syndecan‐4 and promyostatin decline gradually af...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Keller‐Pinter, Aniko, Szabo, Kitti, Kocsis, Tamas, Deak, Ferenc, Ocsovszki, Imre, Zvara, Agnes, Puskas, Laszlo, Szilak, Laszlo, Dux, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Letters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221024/
https://ncbi.nlm.nih.gov/pubmed/30129974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13227
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