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An in vitro method for nephrotoxicity evaluation using HK-2 human kidney epithelial cells combined with biomarkers of nephrotoxicity

The kidney is one of the major target organs for drug-induced toxicity. During drug development, the traditional markers of nephrotoxicity indicate only severe and late damage, which leads to high costs. The new biomarkers are needed for a more sensitive and reliable evaluation of nephrotoxicity, es...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Toxicol Res (Camb)
Main Authors: Qiu, Xuan, Zhou, Xiaobing, Miao, Yufa, Li, Bo
פורמט: Artigo
שפה:Inglês
יצא לאור: Royal Society of Chemistry 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220736/
https://ncbi.nlm.nih.gov/pubmed/30510689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00095f
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