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An in vitro method for nephrotoxicity evaluation using HK-2 human kidney epithelial cells combined with biomarkers of nephrotoxicity
The kidney is one of the major target organs for drug-induced toxicity. During drug development, the traditional markers of nephrotoxicity indicate only severe and late damage, which leads to high costs. The new biomarkers are needed for a more sensitive and reliable evaluation of nephrotoxicity, es...
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| Published in: | Toxicol Res (Camb) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Royal Society of Chemistry
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6220736/ https://ncbi.nlm.nih.gov/pubmed/30510689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00095f |
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