Induced B Cell Development in Adult Mice

We employed the B-Indu-Rag1 model in which the coding exon of recombination-activating gene 1 (Rag1) is inactivated by inversion. It is flanked by inverted loxP sites. Accordingly, B cell development is stopped at the pro/pre B-I cell precursor stage. A B cell-specific Cre recombinase fused to a mut...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Brennecke, Anne-Margarete, Düber, Sandra, Roy, Bishnudeo, Thomsen, Irene, Garbe, Annette I., Klawonn, Frank, Pabst, Oliver, Kretschmer, Karsten, Weiss, Siegfried
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220648/
https://ncbi.nlm.nih.gov/pubmed/30429851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02483
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