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Relaxin Family Member Insulin‐Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models

BACKGROUND: The insulin/insulin‐like growth factor/relaxin family represents a group of structurally related but functionally diverse proteins. The family member relaxin‐2 has been evaluated in clinical trials for its efficacy in the treatment of acute heart failure. In this study, we assessed the r...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Maruyama, Sonomi, Wu, Chia‐Ling, Yoshida, Sumiko, Zhang, Dongying, Li, Pei‐Hsuan, Wu, Fangzhou, Parker Duffen, Jennifer, Yao, Rouan, Jardin, Blake, Adham, Ibrahim M., Law, Ronald, Berger, Joel, Di Marchi, Richard, Walsh, Kenneth
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220528/
https://ncbi.nlm.nih.gov/pubmed/29887522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008441
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