Metformin Improves Neurologic Outcome Via AMP‐Activated Protein Kinase–Mediated Autophagy Activation in a Rat Model of Cardiac Arrest and Resuscitation

BACKGROUND: Sudden cardiac arrest (CA) often results in severe injury to the brain, and neuroprotection after CA has proved to be difficult to achieve. Herein, we sought to investigate the effects of metformin pretreatment on brain injury secondary to CA and cardiopulmonary resuscitation. METHODS AN...

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Bibliografiska uppgifter
I publikationen:J Am Heart Assoc
Huvudupphovsmän: Zhu, Juan, Liu, Kewei, Huang, Kaibin, Gu, Yong, Hu, Yafang, Pan, Suyue, Ji, Zhong
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220525/
https://ncbi.nlm.nih.gov/pubmed/29895585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008389
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