Učitavanje...

Apatinib affect VEGF-mediated cell proliferation, migration, invasion via blocking VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways in cholangiocarcinoma cell

BACKGROUND: Cholangiocarcinoma (CCA) is a form of cancer that easily aggress to contiguous structures. Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2) are increased in majority species of cancers and suppress tumor progression by blocking VEGF/VEGFR2. Apatinib is a highly sele...

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Bibliografski detalji
Izdano u:BMC Gastroenterol
Glavni autori: Huang, Manping, Huang, Bin, Li, Guowen, Zeng, Sainan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220519/
https://ncbi.nlm.nih.gov/pubmed/30400838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-018-0870-3
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