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Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice

BACKGROUND: Inflammation plays a critical role in accelerating the progression of neurodegenerative diseases, such as Alzheimer’s disease (AD) and ataxia telangiectasia (A-T). In A-T mouse models, LPS-induced neuroinflammation advances the degenerative changes found in cerebellar Purkinje neurons bo...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Hui, Chin Wai, Song, Xuan, Ma, Fulin, Shen, Xuting, Herrup, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220455/
https://ncbi.nlm.nih.gov/pubmed/30400801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1338-7
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