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Inheritance of CENP-A nucleosomes during DNA replication requires HJURP

Centromeric chromatin defines the site of kinetochore formation and ensures faithful chromosome segregation. Centromeric identity is epigenetically specified by the incorporation of CENP-A nucleosomes. DNA replication presents a challenge for inheritance of centromeric identity because nucleosomes a...

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發表在:Dev Cell
Main Authors: Zasadzińska, Ewelina, Huang, Jiehuan, Bailey, Aaron O., Guo, Lucie Y., Lee, Nancy S., Srivastava, Shashank, Wong, Kelvin A., French, Bradley T., Black, Ben E., Foltz, Daniel R.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219920/
https://ncbi.nlm.nih.gov/pubmed/30293838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.09.003
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