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IL-1α and not IL-1β drives IL-1R1-dependent neonatal murine sepsis lethality
Sepsis disproportionately affects the very old and the very young. IL-1 signaling is important in innate host defense but may also play a deleterious role in acute inflammatory conditions including sepsis by promulgating life-threatening inflammation. IL-1 signaling is mediated by two distinct ligan...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6219910/ https://ncbi.nlm.nih.gov/pubmed/30305325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801089 |
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