A critical role for ABC transporters in persistent lung inflammation in the development of emphysema after smoke exposure

Macrophage infiltration is common to both emphysema and atherosclerosis, and cigarette smoke down-regulates the macrophage cholesterol efflux transporter ATP binding cassette (ABC)A1. This decreased cholesterol efflux results in lipid-laden macrophages. We hypothesize that cigarette smoke adversely...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Sonett, Jarrod, Goldklang, Monica, Sklepkiewicz, Piotr, Gerber, Adam, Trischler, Jordis, Zelonina, Tina, Westerterp, Marit, Lemaître, Vincent, Okada, Yasunori, D’Armiento, Jeanine
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219826/
https://ncbi.nlm.nih.gov/pubmed/29906247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701381
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