Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells

Immunotherapy approaches stand out as innovative strategies to eradicate tumor cells. Among them, PD-1/PD-L1 immunotherapy is considered one of the most successful advances in the history of cancer immunotherapy. We used our technology of Polypurine reverse Hoogsteen hairpins (PPRHs) for silencing b...

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Bibliographic Details
Published in:PLoS One
Main Authors: Medina Enríquez, Miriam Marlene, Félix, Alex J., Ciudad, Carlos J., Noé, Véronique
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219785/
https://ncbi.nlm.nih.gov/pubmed/30399174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206818
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