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Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5

Metabotropic glutamate receptor 5 (mGlu5) has been implicated in certain forms of synaptic plasticity and cognitive function. mGlu5 knockout (KO) mice and mGlu5 antagonists have been previously used to study the pathophysiology of schizophrenia as they have been shown respectively to display or indu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zeleznikow-Johnston, Ariel M., Renoir, Thibault, Churilov, Leonid, Li, Shanshan, Burrows, Emma L., Hannan, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219561/
https://ncbi.nlm.nih.gov/pubmed/30401923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33929-3
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