T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors

BACKGROUND: Cancer treatments have substantially improved childhood cancer survival but are accompanied by long-term complications, notably chronic inflammatory diseases. We hypothesize that cancer treatments could lead to long-term epigenetic changes in immune cells, resulting in increased prevalen...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Daniel, Sara, Nylander, Vibe, Ingerslev, Lars R., Zhong, Ling, Fabre, Odile, Clifford, Briana, Johnston, Karen, Cohn, Richard J., Barres, Romain, Simar, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219017/
https://ncbi.nlm.nih.gov/pubmed/30400990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0561-5
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