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Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots

Remodeling of the sperm epigenome by lifestyle factors before conception could account for altered metabolism in the next generation offspring. Here, we hypothesized that endurance training changes the epigenome of human spermatozoa. Using small RNA (sRNA) sequencing and reduced representation bisul...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Ingerslev, Lars R., Donkin, Ida, Fabre, Odile, Versteyhe, Soetkin, Mechta, Mie, Pattamaprapanont, Pattarawan, Mortensen, Brynjulf, Krarup, Nikolaj Thure, Barrès, Romain
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785820/
https://ncbi.nlm.nih.gov/pubmed/29416570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0446-7
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