PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

BACKGROUND: The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome activator PA28αβ activates hydrolysis of small nonubiquitinat...

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Vydáno v:BMC Neurosci
Hlavní autoři: Adelöf, Julia, Andersson, My, Porritt, Michelle, Petersen, Anne, Zetterberg, Madeleine, Wiseman, John, Hernebring, Malin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218978/
https://ncbi.nlm.nih.gov/pubmed/30400847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0468-2
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