TPH2 Deficiency Influences Neuroplastic Mechanisms and Alters the Response to an Acute Stress in a Sex Specific Manner

Dysregulations of the central serotoninergic system have been implicated in several psychopathologies, characterized by different susceptibility between males and females. We took advantage of tryptophan hydroxylase 2 (TPH2) deficient rats, lacking serotonin specifically in the brain, to investigate...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Brivio, Paola, Sbrini, Giulia, Peeva, Polina, Todiras, Mihail, Bader, Michael, Alenina, Natalia, Calabrese, Francesca
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218558/
https://ncbi.nlm.nih.gov/pubmed/30425618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00389
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