The Absence of Serotonin in the Brain Alters Acute Stress Responsiveness by Interfering With the Genomic Function of the Glucocorticoid Receptors

Alterations in serotonergic transmission have been related to a major predisposition to develop psychiatric pathologies, such as depression. We took advantage of tryptophan hydroxylase (TPH) 2 deficient rats, characterized by a complete absence of serotonin in the brain, to evaluate whether a vulner...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Sbrini, Giulia, Brivio, Paola, Peeva, Polina Mineva, Todiras, Mihail, Bader, Michael, Alenina, Natalia, Calabrese, Francesca
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278285/
https://ncbi.nlm.nih.gov/pubmed/32547368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00128
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