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Urothelium proliferation is a trigger for renal crystal deposits in a murine lithogenesis model

Most mouse kidney stone models induce nephrocalcinosis rather than urolithiasis. The aim of our study was to find an accelerated experimental model in order to study the early events of stone formation, that is, at the time of crystal binding to intrarenal urothelium. C57B6 mice exposed to vitamin D...

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Publicado en:Sci Rep
Autores principales: Bilbault, Héloïse, Perez, Joëlle, Huguet, Léa, Vandermeersch, Sophie, Placier, Sandrine, Tabibzadeh, Nahid, Frochot, Vincent, Letavernier, Emmanuel, Bazin, Dominique, Daudon, Michel, Haymann, Jean-Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218513/
https://ncbi.nlm.nih.gov/pubmed/30397242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34734-8
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