Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, which develops in the context of fibrosis and cirrhosis caused by chronic inflammation, in turn due to non-alcoholic fatty liver disease (NAFLD), alcohol consumption and/or hepatitis viral infection. An increased number of se...

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Udgivet i:Front Oncol
Main Authors: Kovacovicova, Kristina, Skolnaja, Marianna, Heinmaa, Mihkel, Mistrik, Martin, Pata, Pille, Pata, Illar, Bartek, Jiri, Vinciguerra, Manlio
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218402/
https://ncbi.nlm.nih.gov/pubmed/30425964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00459
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