Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention and treatment. A minority of affected patients develops inflammation, subsequently fibrosis, cirrhosis and hepatocellular carcinoma (HCC). HCC is a leading cause o...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Raffaele, Marco, Kovacovicova, Kristina, Frohlich, Jan, Lo Re, Oriana, Giallongo, Sebastiano, Oben, Jude A., Faldyna, Martin, Leva, Lenka, Giannone, Antonino Giulio, Cabibi, Daniela, Vinciguerra, Manlio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034117/
https://ncbi.nlm.nih.gov/pubmed/33832488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-021-00731-0
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