Differential Gene Expression in Macrophages From Human Atherosclerotic Plaques Shows Convergence on Pathways Implicated by Genome-Wide Association Study Risk Variants

OBJECTIVE—: Plaque macrophages are intricately involved in atherogenesis and plaque destabilization. We sought to identify functional pathways in human plaque macrophages that are differentially regulated in respect of (1) plaque stability and (2) lipid content. We hypothesized that differentially r...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Principais autores: Chai, Joshua T., Ruparelia, Neil, Goel, Anuj, Kyriakou, Theodosios, Biasiolli, Luca, Edgar, Laurienne, Handa, Ashok, Farrall, Martin, Watkins, Hugh, Choudhury, Robin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Translational Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217969/
https://ncbi.nlm.nih.gov/pubmed/30354237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311209
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