Differential Gene Expression in Macrophages From Human Atherosclerotic Plaques Shows Convergence on Pathways Implicated by Genome-Wide Association Study Risk Variants

OBJECTIVE—: Plaque macrophages are intricately involved in atherogenesis and plaque destabilization. We sought to identify functional pathways in human plaque macrophages that are differentially regulated in respect of (1) plaque stability and (2) lipid content. We hypothesized that differentially r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arterioscler Thromb Vasc Biol
Päätekijät: Chai, Joshua T., Ruparelia, Neil, Goel, Anuj, Kyriakou, Theodosios, Biasiolli, Luca, Edgar, Laurienne, Handa, Ashok, Farrall, Martin, Watkins, Hugh, Choudhury, Robin P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2018
Aiheet:
Translational Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217969/
https://ncbi.nlm.nih.gov/pubmed/30354237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311209
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