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Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis

BACKGROUND: Pericytes are vascular mural cells and are embedded in the basement membrane of the microvasculature. Recent studies suggest a role for pericytes in lipopolysaccharide (LPS)-induced microvascular dysfunction and mortality, but the mechanisms of pericyte loss in sepsis are largely unknown...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Autores principales: Li, Pengfei, Zhou, Yue, Goodwin, Andrew J, Cook, James A, Halushka, Perry V, Zhang, Xian K, Wilson, Carole L, Schnapp, Lynn M, Zingarelli, Basilia, Fan, Hongkuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217724/
https://ncbi.nlm.nih.gov/pubmed/30053030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy451
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