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Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis

Previous studies have implicated a role of heterotrimeric Gα(i) proteins in lipopolysaccharide (LPS) -induced inflammatory responses. We hypothesized that Toll-like receptor (TLR) signaling regulates Gα(i) proteins, which are anti-inflammatory in endotoxemia and polymicrobial sepsis. Raw 264.7 cells...

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Detalhes bibliográficos
Main Authors: Fan, Hongkuan, Li, Pengfei, Zingarelli, Basilia, Borg, Keith, Halushka, Perry V., Birnbaumer, Lutz, Cook, James A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046305/
https://ncbi.nlm.nih.gov/pubmed/21255617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.01.012
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