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Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Gα(i) proteins

Heterotrimeric G(i) proteins play a role in signalling activated by lipopolysaccharide (LPS), Staphylococcus aureus (SA) and group B streptococci (GBS), leading to production of inflammatory mediators. We hypothesized that genetic deletion of G(i) proteins would alter cytokine and chemokine producti...

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Bibliografiske detaljer
Main Authors: Fan, Hongkuan, Williams, David L, Zingarelli, Basilia, Breuel, Kevin F, Teti, Giuseppe, Tempel, George E, Spicher, Karsten, Boulay, Guylain, Birnbaumer, Lutz, Halushka, Perry V, Cook, James A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265979/
https://ncbi.nlm.nih.gov/pubmed/17484771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02619.x
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