PDTM-47. REAL TIME IN VIVO MONITORING OF 18F-LABELED PANOBINOSTAT PHARMAKOKINETICS FOR TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) VIA CONVECTION ENHANCED DELIVERY (CED)

Diffuse intrinsic pontine glioma (DIPG) is a universally fatal tumor of childhood with median survival of one year: an initially good response to radiation therapy is invariably followed by recurrence. Recent promise comes from the use of histone deacetylase complex (HDAC) inhibitors which normalize...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Tosi, Umberto, Kommidi, Harikrishna, Bhanu Maachani, Uday, Marnell, Christopher, Guo, Hua, Schweitzer, Melanie, Ting, Richard, Souweidane, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217474/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.886
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