EXTH-36. BIFUNCTIONAL RNA NANOPARTICLES INDUCE ANTITUMOR IMMUNE RESPONSES AND ALLOW MRI-BASED DETECTION OF DENDRITIC CELL MIGRATION AS A BIOMARKER OF ANTITUMOR IMMUNE RESPONSE

BACKGROUND: Cancer vaccines are a promising approach to personalized cancer immunotherapy, but the lack of meaningful biomarkers of patient response to treatment limits their development. We recently reported in a randomized and blinded pilot clinical trial that RNA-pulsed dendritic cells (DCs) comb...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Grippin, Adam, Wummer, Brandon, Sayour, Elias, Monsalve, Adam, Fillingim, Matthew, Dyson, Kyle, Wildes, Tyler, Dobson, Jon, Mitchell, Duane
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217320/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.385
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