TMIC-12. TUMOR-HOMING RNA-NANOPARTICLES REPROGRAM IMMUNE CELLS IN THE BRAIN TUMOR MICROENVIRONMENT

BACKGROUND: Brain tumors are particularly difficult to treat due to their relative isolation behind the blood brain barrier. Cytotoxic T cells elicited by cancer vaccines are capable of penetrating this barrier, but are limited by innate immune cells in tumor microenvironments that inhibit T cell fu...

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Publicado no:Neuro Oncol
Main Authors: Grippin, Adam, Mendez-Gomez, Hector, Wummer, Brandon, Wildes, Tyler, Dyson, Kyle, Valladares, Daniel, Dobson, Jon, Sayour, Elias, Mitchell, Duane
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216349/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1071
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