EXTH-32. TRANSGENIC EXPRESSION OF IL15 IMPROVES THE EFFICACY OF CAR T CELLS IN AN IMMUNE COMPETENT GLIOBLASTOMA MODEL

BACKGROUND: Malignant gliomas (MG) are the most common and difficult-to-treat adult brain tumors. The outstanding efficacy of chimeric antigen receptor (CAR)-modified T cells against hematological malignancies gives hope that they can be programmed to target and eradicate solid tumors like MG. We re...

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Publicado no:Neuro Oncol
Main Authors: Pituch, Katarzyna, Zannikou, Markella, Ilut, Liliana, Chen, Christopher, Lesniak, Maciej, Gottschalk, Stephen, Krenciute, Giedre, Balyasnikova, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217302/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.381
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