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CBMT-34. TARGETING THE RNA-PROCESSING GENE MAGOH AS A NOVEL THERAPY FOR MEDULLOBLASTOMA

We have proposed that microcephaly-producing mutations identify genes required for growth in the nervous system that may be new targets for brain tumor treatment. We tested this hypothesis by deleting the RNA-processing gene Magoh during cerebellar development and medulloblastoma pathogenesis. Magoh...

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Pubblicato in:Neuro Oncol
Autori principali: Ocasio, Jennifer, Liu, Hedi, Gershon, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217153/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.153
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