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MEDU-31. GSK-3 PROMOTES PROLIFERATION DURING POSTNATAL CEREBELLAR DEVELOPMENT AND MAY BE TARGETED IN MEDULLOBLASTOMA THERAPY
We examined the role of the multi-pathway regulator GSK-3 in medulloblastoma pathogenesis in light of prior studies showing that GSK-3 restricts the proliferation of cerebral neural progenitors, preventing overgrowth. Importantly, GSK-3 regulates diverse intracellular processes, including signaling...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475151/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.181 |
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