MEDU-31. GSK-3 PROMOTES PROLIFERATION DURING POSTNATAL CEREBELLAR DEVELOPMENT AND MAY BE TARGETED IN MEDULLOBLASTOMA THERAPY

We examined the role of the multi-pathway regulator GSK-3 in medulloblastoma pathogenesis in light of prior studies showing that GSK-3 restricts the proliferation of cerebral neural progenitors, preventing overgrowth. Importantly, GSK-3 regulates diverse intracellular processes, including signaling...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Ocasio, Jennifer, Meidinger, Jessica, Gershon, Timothy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475151/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.181
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