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CBMT-06. LOWER GRADE ISOCITRATE DEHYDROGENASE (IDH) MUTANT GLIOMAS METABOLICALLY MIMICKING GLIOBLASTOMA (GBM) EXPRESS HIGHER R:S 2-HYDROXYGLUTARATE RATIOS RELATIVE TO NON-GBM-MIMICKING IDH MUTANT GLIOMAS
BACKGROUND: Glioma patients continue to carry a very poor prognosis despite maximal therapy, urging for the development of novel therapies. Previous studies have identified mutations of metabolic enzymes directly regulating cellular metabolism, specifically, isocitrate dehydrogenase (IDH1/2) mutatio...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216969/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.125 |
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