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CADD-21. PROTEASOME INHIBITION IS A TARGETED THERAPY FOR PTEN-DEFICIENT GLIOBLASTOMAS
One of the most common genetic alterations in glioblastoma (30–40%) occurs in the PTEN (phosphatase and tensin homolog) tumor suppressor gene, where loss of function has been mechanistically linked to increased tumor cell invasion, and to a lack of radio- and chemo-therapy response. To identify new...
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| Publicado no: | Neuro Oncol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216841/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1165 |
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