CSIG-36. INVOLVEMENT OF microRNAs 221/222-3p IN THE REGULATION OF PROGRAMMED CELL DEATH 10 (PDCD10) GENE IN GLIOBLASTOMA

INTRODUCTION: FAT1 gene is localized at chromosome 4q35.2 encoding a 506KDa. Here in our study we are characterizing the role of FAT1 in primary brain tumors. MiR-221-3p/222-3p reported to have oncogenic role and targets tumor suppressors (e.g. PDCD10, PTEN, PUMA etc.) in many cancers including GBM....

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Vydáno v:Neuro Oncol
Hlavní autoři: Malik, Nargis, Chattopadhyay, Parthaprasad, Sarkar, Chitra, Suri, Ashish, Sinha, Subrata, Chosdol, Kunzang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216771/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.202
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