Clonal mutations in primary human glial tumors: evidence in support of the mutator hypothesis

BACKGROUND: A verifiable consequence of the mutator hypothesis is that even low grade neoplasms would accumulate a large number of mutations that do not influence the tumor phenotype (clonal mutations). In this study, we have attempted to quantify the number of clonal mutations in primary human glio...

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Autors principals: Misra, Anjan, Chattopadhyay, Parthaprasad, Chosdol, Kunzang, Sarkar, Chitra, Mahapatra, Ashok K, Sinha, Subrata
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190769/
https://ncbi.nlm.nih.gov/pubmed/17925012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-190
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