CSIG-23. miR-146a PREDICTS BETTER OVERALL SURVIVAL AND ACTS AS A TEMOZOLOMIDE (TMZ) SENSITIZER THROUGH TARGETING MULTIPLE SIGNALING PATHWAYS IN GLIOBLASTOMA

BACKGROUND: Glioblastomas (GBMs) are the most aggressive primary brain tumors, with an average survival of less than 15 months. microRNAs (miRNAs) are emerging as promising, novel prognostic biomarkers in GBM. miRNA-146a acts as a tumor suppressor in different cancer types. This purpose of this stud...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Cui, Tiantian, Hlavin Bell, Erica, Liu, Kevin, McElroy, Joseph, Geurts, Marjolein, Gray, Ashley, Becker, Aline, Fleming, Jessica, Beyer, Sasha, Haque, Jahar, Robe, Pierre, Chakravarti, Arnab
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216673/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.189
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