DRES-20. THE TNF RECEPTOR FAMILY MEMBER Fn14 IS HIGHLY EXPRESSED IN RECURRENT GLIOBLASTOMA (GBM) AND IN GBM PATIENT-DERIVED XENOGRAFTS WITH ACQUIRED TEMOZOLOMIDE RESISTANCE

INTRODUCTION: The current standard-of-care for patients with glioblastoma (GBM) consists of maximal safe surgical resection followed by high-dose radiation and concomitant oral chemotherapy using the DNA-alkylating agent temozolomide (TMZ). Despite this combination treatment, tumor recurrence is nea...

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Pubblicato in:Neuro Oncol
Autori principali: Hersh, David, Heath, Jonathan, Woodworth, Graeme, Tran, Nhan, Winkles, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216626/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.327
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