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DDIS-15. A NOVEL DOPAMINE RECEPTOR 3 ANTAGONIST INHIBITS THE GROWTH OF PRIMARY AND TEMOZOLOMIDE RESISTANT GLIOBLASTOMA CELLS

Glioblastoma (GBM) is the most common, lethal primary adult brain tumor with patient survival of only 14 months. The location and invasion of GBM leads to rapid recurrence after therapy. The standard of care chemotherapy is DNA damaging agent temozolomide (TMZ), to which resistance is common and is...

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Vydáno v:Neuro Oncol
Hlavní autoři: Scott, Sarah, Libby, Catherine, Hjelmeland, Anita
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.294
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