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Geometry of the Sample Frequency Spectrum and the Perils of Demographic Inference
The sample frequency spectrum (SFS), which describes the distribution of mutant alleles in a sample of DNA sequences, is a widely used summary statistic in population genetics. The expected SFS has a strong dependence on the historical population demography and this property is exploited by popular...
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| Udgivet i: | Genetics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216588/ https://ncbi.nlm.nih.gov/pubmed/30064984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300733 |
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