DRES-14. PROTEIN AGGREGATE FORMATION PREDICTS CLINICAL RESPONSES TO EGFR TKIs

BACKGROUND: EGFR tyrosine kinase inhibitors (TKIs) have thus-far not shown clinical benefit for glioma patients, which is in stark contrast to the benefit observed for patients with EGFR-mutated pulmonary adenocarcinomas (PA). We performed functional analysis on various EGFR-mutation constructs to b...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: French, Pim, Gao, Ya, de Wit, Maurice, Mercieca, Darlene, de Heer, Iris, van Royen, Martin, Aerts, Joachim, Sillevis Smitt, Peter
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216542/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.321
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