ACTR-53. STEAM / EORTC 1608: STUDY OF TG02 IN ELDERLY NEWLY DIAGNOSED OR ADULT RELAPSED PATIENTS WITH ANAPLASTIC ASTROCYTOMA OR GLIOBLASTOMA - A PHASE 1B STUDY

BACKGROUND: TG02 is an oral multi-cyclin dependent kinase (CDK) inhibitor that is thought to inhibit tumor growth mainly through CDK9-dependent depletion of oncoproteins such as MCL-1 and MYC. MCL-1 and MYC are frequently overexpressed in glioblastoma (up to 80%). Several studies including analyses...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Le Rhun, Emilie, Parrott, Tract, Gorlia, Thierry, Fournier, Beatrice, Estok, Tom, Weller, Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2018
विषय:
Abstracts
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216429/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.085
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