ACTR-69. PHASE I TRIAL OF TG02 PLUS DOSE-DENSE OR METRONOMIC TEMOZOLOMIDE FOR ADULTS WITH RECURRENT ANAPLASTIC ASTROCYTOMA AND GLIOBLASTOMA

BACKGROUND: Most therapies for recurrent high grade gliomas have not been successful, largely due to the complexity of the disease. Our preclinical studies have demonstrated the anti-glioma effects of TG02 and the synergy with temozolomide (TMZ) through modulation of transcription and metabolism. We...

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Publicado en:Neuro Oncol
Main Authors: Wu, Jing, Bryla, Christine, McCoy, Ann, Lisa, Boris, Garren, Nancy, Siegel, Christine, Grajkowska, Ewa, Theeler, Brett, Park, Deric M, Parrott, Tracy, Armstrong, Terri S, Yuan, Ying, Gilbert, Mark R
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692827/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.056
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