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EXTH-80. IMPAIRED PARP1 DNA REPAIR DEFINES CHEMO-SENSITIVITY IN IDH1-MUTATED CELL

BACKGROUND: Mutations in isocitrate dehydrogenase (IDH1/2) are the most prevalent genetic deficiency in lower grade gliomas. IDH-mutated in glioma exhibits better clinical outcomes with longer patient survival, as well as greater sensitivity to chemotherapy. In the present study, we explored the mol...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lu, Yanxin, Liu, Yang, Gilbert, Mark, Wu, Jing, Yang, Chunzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216391/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.427
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